WD repeat-containing protein DWA1 (DWA1), Recombinant Protein
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WD repeat-containing protein DWA1 (DWA1), Recombinant Protein

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Cat: RP00999
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana WD repeat-containing protein DWA1 (DWA1)
Product Gene Name
DWA1 recombinant protein
Product Synonym Gene Name
DWA1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MYGDATNWNE DEYRESILKE REIETRTVFR TAWAPPARIS NPDAFVVASS DGTLAFHSLN SLVSQSASFG YSKGQDVMVA EPERVVRAHE GPAYDVKFYG EDEDALLLSC GDDGRVRGWK WREFAESDVS LHLKENHLKP LLELINPQHK GPWGALSPMP EINAMSVDPQ SGSVFTAAGD SCAYCWDVES GKIKMTFKGH SDYLHTVVSR SSASQILTGS EDGTARIWDC KTGKCVKVIG SQDKKSRLRV SSMALDGSES WLVCGQGKNL ALWNLPASEC VQTIPIPAHV QDVMFDEKQI LTVGAEPLLR RFDLNGALLS QIHCAPCSVF SISLHPAGVV AVGGYGGIVD VISQFGSHLC TFRSSSL
Sequence Positions
1-367, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
40,073 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

NCBI/Uniprot Data

NCBI Accession #
NP_849989.1
NCBI GI #
30680669
NCBI GenBank Nucleotide #
NM_179658.4
NCBI GeneID
816462
NCBI Official Full Name
DWD (DDB1-binding WD40 protein) hypersensitive to ABA 1
NCBI Official Symbol
DWA1
NCBI Official Synonym Symbols
AtTHO6; DWD (DDB1-binding WD40 protein) hypersensitive to ABA 1; F27F23.25; THO6
NCBI Protein Information
DWD (DDB1-binding WD40 protein) hypersensitive to ABA 1
NCBI Summary
This gene is predicted to encode a protein with a DWD motif. It can bind to DDB1a in Y2H assays, and DDB1b in co-IP assays, and may be involved in the formation of a CUL4-based E3 ubiquitin ligase. Encodes a component of the putative Arabidopsis THO/TREX complex: THO1 or HPR1 (At5g09860), THO2 (At1g24706), THO3 or TEX1 (At5g56130), THO5 (At5g42920, At1g45233), THO6 (At2g19430), and THO7 (At5g16790, At3g02950). THO/TREX complexes in animals have been implicated in the transport of mRNA precursors. Mutants of THO3/TEX1, THO1, THO6 accumulate reduced amount of small interfering (si)RNA, suggesting a role of the putative Arabidopsis THO/TREX in siRNA biosynthesis.
UniProt Gene Name
THO6
UniProt Synonym Gene Names
DWA1; THOC6; AtTHO6
UniProt Protein Name
THO complex subunit 6
UniProt Synonym Protein Names
Protein DWD HYPERSENSITIVE TO ABA 1; WD repeat-containing protein DWA1
UniProt Primary Accession #
Q8L4M1
UniProt Secondary Accession #
O64576
UniProt Related Accession #
Q8L4M1
UniProt Comments
Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export.

For research use only, not for clinical use.