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Villin-1 (VLN1), Recombinant Protein
Cat: RP01779
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Villin-1 (VLN1) , partial
Product Gene Name
VLN1 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
102,950 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Villin
NCBI/Uniprot Data
NCBI Accession #
NP_001324173.1
NCBI GI #
1063705236
NCBI GenBank Nucleotide #
NM_001336228.1
NCBI GeneID
817539
NCBI Official Full Name
villin-like 1
NCBI Official Symbol
VLN1
NCBI Official Synonym Symbols
ATVLN1; F6K5.2; F6K5_2; villin 1; villin-like 1
NCBI Protein Information
villin-like 1
NCBI Summary
Encodes a ubiquitously expressed villin-like protein, whose mRNA may be alternatively processed. Villin belongs to a superfamily of actin binding proteins called the villin/gelsolin family. Animal villins are involved in actin binding. VLN1 protein co-localizes with actin filaments in several assays. VLN1 binds and bundles F-actin in a calcium-independent manner. It does not nucleate, cap or sever actin filaments and it stabilizes actin filaments, protecting them from ADF-mediated depolymerization.
UniProt Gene Name
VLN1
UniProt Protein Name
Villin-1
UniProt Primary Accession #
O81643
UniProt Secondary Accession #
O82367; Q9SIK8
UniProt Related Accession #
O81643
UniProt Comments
Binds actin and actin filament bundles in a Ca2+/calmodulin-insensitive manner, but is unable to sever, cap, and nucleate actin filament formation in vitro. Does not protect individual filaments from severing by VLN3 (AC O81645).
For research use only, not for clinical use.