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UDP-glucuronate 4-epimerase 4 (GAE4), Recombinant Protein
Cat: RP00206
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana UDP-glucuronate 4-epimerase 4 (GAE4)
Product Synonym Names
Recombinant UDP-glucuronate 4-epimerase 4 (GAE4); UDP-glucuronate 4-epimerase 4 EC= 5.1.3.6; UDP-glucuronic acid epimerase 4; AtUGlcAE1
Product Gene Name
GAE4 recombinant protein
Product Synonym Gene Name
GAE4; UGlcAE1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MSRLDDIPSS PGKFKMEKSS YLHRLRFQSS LTKFAFFSFF LLCLISLLFL RSPPSINPSS PSDPSRRSLR TNTYGGPAWE KRLRSSARIR TSTNNGITVL VTGAAGFVGT HVSAALKRRG DGVIGLDNFN DYYDPSLKRA RRALLERSGI FIVEGDINDV ELLRKLFKIV SFTHVMHLAA QAGVRYAMEN PSSYVHSNIA GFVNLLEICK SVNPQPAIVW ASSSSVYGLN TKVPFSEKDK TDQPASLYAA TKKAGEEIAH TYNHIYGLSL TGLRFFTVYG PWGRPDMAYF FFTKDILKGK SISIFESANH GTVARDFTYI DDIVKGCLAA LDTAEKSTGS GGKKRGPAQL RVFNLGNTSP VPVSDLVRIL ERQLKVKAKK NLIKMPRNGD VPFTHANISL AQRELGYKPT TDLQTGLKKF VRWYLSYYSG DKKAAAR
Sequence Positions
1-437
Chromosome Location
Chromosome: 2; NC_003071.7 (18682081..18684042). Location: chromosome: 2
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
48,536 Da
Storage
Store at -20℃. For extended storage, store at -20 or -80℃.
Protein Family
UDP-glucuronate 4-epimerase
NCBI/Uniprot Data
NCBI Accession #
NP_182056.1
NCBI GI #
15225451
NCBI GenBank Nucleotide #
NM_130094.2
NCBI GeneID
819139
NCBI Official Full Name
UDP-D-glucuronate 4-epimerase 4
NCBI Official Symbol
GAE4
NCBI Official Synonym Symbols
F4L23.18; GAE4; UDP-D-glucuronate 4-epimerase 4
NCBI Protein Information
UDP-D-glucuronate 4-epimerase 4
NCBI Summary
UDP-D-glucuronate 4-epimerase
UniProt Gene Name
GAE4
UniProt Synonym Gene Names
UGlcAE1; AtUGlcAE1
UniProt Protein Name
UDP-glucuronate 4-epimerase 4
UniProt Synonym Protein Names
UDP-glucuronic acid epimerase 4
UniProt Entry Name
GAE4_ARATH
UniProt Primary Accession #
O22141
UniProt Related Accession #
A84889
UniProt Comments
Function: Involved in the synthesis of the negatively charged monosaccharide that forms the backbone of pectic cell wall components.Catalytic activity: UDP-glucuronate = UDP-D-galacturonate.Enzyme regulation: Activated by glycerol, not effected by dimethyl sulfoxide and inhibited by high concentration of monovalent salts, UDP-xylose, UDP-arabinose or UDP.Subunit structure: Homodimer Probable.Subcellular location: Golgi apparatus › Golgi stack membrane; Multi-pass membrane protein Potential. Tissue specificity: In roots, leaves, siliques, flowers, pollen and stems.Sequence similarities: Belongs to the sugar epimerase family.Biophysicochemical propertiesKinetic parameters:Equilibrium between UDP-glucuronate and UDP-D-galacturonate established at 1:1.9. No activity with UDP-Galactose, UDP-Glucose, UDP-arabinose, UDP-Xylose, CDP-glucose or GDP-manose.KM=0.72 mM for UDP-glucuronatepH dependence:Optimum pH is 7.5. Active from pH 6.8 to 8.2.Temperature dependence:Active between 20 and 55 degrees Celsius.
For research use only, not for clinical use.