NCBI Accession #
NP_567478.1
NCBI GenBank Nucleotide #
NM_117680.4
NCBI Official Full Name
Cysteine proteinases superfamily protein
NCBI Official Symbol
ESD4
NCBI Official Synonym Symbols
ATESD4; DL3980W; EARLY IN SHORT DAYS 4; FCAALL.406
NCBI Protein Information
Cysteine proteinases superfamily protein
NCBI Summary
EARLY IN SHORT DAYS 4 Arabidopsis mutant shows extreme early flowering and alterations in shoot development. It encodes a SUMO protease, located predominantly at the periphery of the nucleus. Accelerates the transition from vegetative growth to flowering. Probably acts in the same pathway as NUA in affecting flowering time, vegetative and inflorescence development.
UniProt Synonym Gene Names
AtESD4
UniProt Protein Name
Ubiquitin-like-specific protease ESD4
UniProt Synonym Protein Names
Protein EARLY IN SHORT DAYS 4; AtESD4
UniProt Primary Accession #
Q94F30
UniProt Secondary Accession #
O23439; Q70G10; Q7DLT0; B9DFG4
UniProt Related Accession #
Q94F30
UniProt Comments
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMOs to their mature forms and deconjugation of SUMO from targeted proteins. Cleaves precursors of SUM1 and SUM2, but not of SUM3 or SUM5. Able to release SUM1 and SUM2 from conjugates, but unable to cleave SUM3. Acts predominantly as an isopeptidase, cleaving SUMO-conjugated proteins better than SUMO peptides. Plays an important role in the control of flowering time.