NCBI Accession #
NP_565693.1
NCBI GenBank Nucleotide #
NM_128566.4
NCBI Official Full Name
ubiquitin-activating enzyme 1
NCBI Official Symbol
UBA1
NCBI Official Synonym Symbols
ATUBA1; MODIFIER OF SNC1 5; MOS5; T27E13.15; T27E13_15; ubiquitin-activating enzyme 1
NCBI Protein Information
ubiquitin-activating enzyme 1
NCBI Summary
Encodes a ubiquitin-activating enzyme (E1), involved in the first step in conjugating multiple ubiquitins to proteins targeted for degradation. Gene is expressed in most tissues examined. Mutant is able to revert the constitutive defense responses phenotype of snc1, which indicates the gene is involved in defense response. It also indicates that ubiquitination plays a role in plant defense signalling.
UniProt Synonym Gene Names
MOS5; AtUBA1
UniProt Protein Name
Ubiquitin-activating enzyme E1 1
UniProt Synonym Protein Names
Protein MODIFIER OF SNC1 5
UniProt Primary Accession #
P93028
UniProt Secondary Accession #
Q8RX82
UniProt Related Accession #
P93028
UniProt Comments
Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP.