NCBI Accession #
XP_002452566.1
NCBI GenBank Nucleotide #
XM_002452521.2
NCBI Official Full Name
U1 small nuclear ribonucleoprotein C-2
NCBI Official Symbol
LOC8068597
NCBI Official Synonym Symbols
U1C-2; U1-C-2
NCBI Protein Information
U1 small nuclear ribonucleoprotein C-2
UniProt Gene Name
Sb04g028260
UniProt Synonym Gene Names
U1 snRNP C-2; U1-C-2; U1C-2
UniProt Protein Name
U1 small nuclear ribonucleoprotein C-2
UniProt Primary Accession #
C5XYW4
UniProt Related Accession #
C5XYW4
UniProt Comments
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.