NCBI Accession #
NP_195705.1
NCBI GenBank Nucleotide #
NM_120158.2
NCBI Official Full Name
tryptophan N-hydroxylase 1
NCBI Official Symbol
CYP79B2
NCBI Official Synonym Symbols
cytochrome P450; family 79; polypeptide 2; subfamily B; T5J17.120; T5J17_120
NCBI Protein Information
tryptophan N-hydroxylase 1
NCBI Summary
Belongs to cytochrome P450 and is involved in tryptophan metabolism. Converts Trp to indo-3-acetaldoxime (IAOx), a precursor to IAA and indole glucosinolates.
UniProt Gene Name
CYP79B2
UniProt Protein Name
Tryptophan N-monooxygenase 1
UniProt Synonym Protein Names
Cytochrome P450 79B2; Tryptophan N-hydroxylase 1
UniProt Entry Name
C79B2_ARATH
UniProt Primary Accession #
O81346
UniProt Secondary Accession #
Q9SMR0
UniProt Related Accession #
O81346
UniProt Comments
Function: Converts tryptophan to indole-3-acetaldoxime, a precursor for tryptophan derived glucosinolates and indole-3-acetic acid (IAA).Catalytic activity: L-tryptophan + 2 NADPH + 2 O2 = indole-3-acetaldoxime + 2 NADP+ + 3 H2O + CO2.Cofactor: Heme group By similarity.Subcellular location: Membrane; Single-pass membrane protein Potential. Tissue specificity: Found in all tissues tested. Highest expression in roots, and low expression in stem.Sequence similarities: Belongs to the cytochrome P450 family.Biophysicochemical propertiesKinetic parameters:KM=21 µM for tryptophan