NCBI Accession #
NP_001078527.1
NCBI GenBank Nucleotide #
NM_001085058.1
NCBI Official Full Name
transcriptional activator DEMETER
NCBI Official Synonym Symbols
AT5G04570; AT5G04580; DEMETER; DME; T32M21.160; T32M21_160
NCBI Protein Information
transcriptional activator DEMETER
UniProt Protein Name
Transcriptional activator DEMETER
UniProt Synonym Protein Names
DNA glycosylase-related protein DME
UniProt Entry Name
DME_ARATH
UniProt Primary Accession #
Q8LK56
UniProt Secondary Accession #
Q1WEY5; Q84TL4; Q9LZ67; Q9LZ68; Q9LZ69
UniProt Related Accession #
Q8LK56
UniProt Comments
Transcriptional activator involved in gene imprinting. Catalyzes the release of 5-methylcytosine (5-meC) from DNA by a glycosylase/lyase mechanism. Allows the expression of the maternal copy of the imprinted MEA gene before fertilization, possibly by antagonizing or suppressing DNA methylation on target promoter. Probably acts by nicking the MEA promoter. Required for stable reproducible patterns of floral and vegetative development.