NCBI Accession #
NP_192720.2
NCBI GenBank Nucleotide #
NM_117050.3
NCBI Official Full Name
basic helix-loop-helix (bHLH) DNA-binding superfamily protein
NCBI Official Synonym Symbols
AtTT8; BHLH42; F17A8.170; F17A8_170; TRANSPARENT TESTA 8
NCBI Protein Information
basic helix-loop-helix (bHLH) DNA-binding superfamily protein
NCBI Summary
TT8 is a regulation factor that acts in a concerted action with TT1, PAP1 and TTG1 on the regulation of flavonoid pathways, namely proanthocyanidin and anthocyanin biosynthesis. Affects dihydroflavonol 4-reductase gene expression. It is thought that a ternary complex composed of TT2, TT8 and TTG1 is necessary for correct expression of BAN in seed endothelium. Also important for important for marginal trichome development. It binds the promoter of both AT3G26790 and AT1G28300.
UniProt Synonym Gene Names
BHLH42; EN32; AtbHLH42; bHLH 42
UniProt Protein Name
Transcription factor TT8
UniProt Synonym Protein Names
Basic helix-loop-helix protein 42; AtbHLH42; bHLH 42; Protein TRANSPARENT TESTA 8; Transcription factor EN 32; bHLH transcription factor bHLH042
UniProt Primary Accession #
Q9FT81
UniProt Secondary Accession #
Q1PEA5; Q9SZ97; A0MF61
UniProt Related Accession #
Q9FT81
UniProt Comments
Transcription activator, when associated with MYB75/PAP1 or MYB90/PAP2. Involved in the control of flavonoid pigmentation. Plays a key role in regulating leucoanthocyanidin reductase (BANYULS) and dihydroflavonol-4-reductase (DFR). Not required for leucoanthocyanidin dioxygenase (LDOX) expression.