NCBI Accession #
NP_200133.2
NCBI GenBank Nucleotide #
NM_124700.3
NCBI Official Full Name
basic helix-loop-helix (bHLH) DNA-binding superfamily protein
NCBI Official Symbol
SPCH
NCBI Official Synonym Symbols
MFH8.15; SPEECHLESS
NCBI Protein Information
basic helix-loop-helix (bHLH) DNA-binding superfamily protein
NCBI Summary
Encodes a basic helix-loop-helix (bHLH) transcription factor that is necessary and sufficient for the asymmetric divisions that establish the stomatal lineage in Arabidopsis thaliana. Expression of SPCH in young epidermal cells allows these cells to make asymmetric divisions. SPCH is a substrate of a kinase MPK3 and MPK6. Its transcript levels change after inducing MUTE expression in a mute background.
UniProt Synonym Gene Names
BHLH98; EN19; AtbHLH98; bHLH 98
UniProt Protein Name
Transcription factor SPEECHLESS
UniProt Synonym Protein Names
Basic helix-loop-helix protein 98; AtbHLH98; bHLH 98; Transcription factor EN 19; bHLH transcription factor bHLH098
UniProt Primary Accession #
Q700C7
UniProt Secondary Accession #
Q9FK20
UniProt Related Accession #
Q700C7
UniProt Comments
Transcription factor. Together with FMA and MUTE, regulates the stomata formation. Required for the initiation and the formation of stomata, by promoting the first asymmetric cell divisions.