NCBI Accession #
NP_565991.2
NCBI GenBank Nucleotide #
NM_129862.3
NCBI Official Full Name
phytochrome interacting factor 4
NCBI Official Symbol
PIF4
NCBI Official Synonym Symbols
AtPIF4; MFL8.13; MFL8_13; phytochrome interacting factor 4; SRL2
NCBI Protein Information
phytochrome interacting factor 4
NCBI Summary
Isolated as a semidominant mutation defective in red -light responses. Encodes a nuclear localized bHLH protein that interacts with active PhyB protein. Negatively regulates phyB mediated red light responses. Involved in shade avoidance response. Protein abundance is negatively regulated by PhyB.
UniProt Synonym Gene Names
BHLH9; EN102; SRL2; AtbHLH9; bHLH 9
UniProt Protein Name
Transcription factor PIF4
UniProt Synonym Protein Names
Basic helix-loop-helix protein 9; AtbHLH9; bHLH 9; Phytochrome-interacting factor 4; Short under red-light 2; Transcription factor EN 102; bHLH transcription factor bHLH009
UniProt Primary Accession #
Q8W2F3
UniProt Secondary Accession #
A5Y7D4; A5Y7D5; A5Y7D6; A5Y7D7; A5Y7D8; A5Y7D9; A5Y7E0; A5Y7E1; A5Y7E2; A5Y7E3; A5Y7E4
UniProt Related Accession #
Q8W2F3
UniProt Comments
Transcription factor acting negatively in the phytochrome B signaling pathway. May regulate the expression of a subset of genes involved in cell expansion by binding to the G-box motif . Activated by CRY1 and CRY2 in response to low blue light (LBL) by direct binding at chromatin on E-box variant 5'-CA[CT]GTG-3' to stimulate specific gene expression to adapt global physiology (e.g. hypocotyl elongation in low blue light) (PubMed:26724867).