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Transcription factor HY5 (HY5), Recombinant Protein
Cat: RP00101
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Transcription factor HY5 (HY5)
Product Gene Name
HY5 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MQEQATSSLA ASSLPSSSER SSSSAPHLEI KEGIESDEEI RRVPEFGGEA VGKETSGRES GSATGQERTQ ATVGESQRKR GRTPAEKENK RLKRLLRNRV SAQQARERKK AYLSELENRV KDLENKNSEL EERLSTLQNE NQMLRHILKN TTGNKRGGGG GSNADASL
Sequence Positions
1-168, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
18,463 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Transcription factor
NCBI/Uniprot Data
NCBI Accession #
NP_568246.1
NCBI GI #
18416509
NCBI GenBank Nucleotide #
NM_121164.5
NCBI GeneID
830996
NCBI Official Full Name
Basic-leucine zipper (bZIP) transcription factor family protein
NCBI Official Symbol
HY5
NCBI Official Synonym Symbols
BZIP TRANSCRIPTION FACTOR HY5; ELONGATED HYPOCOTYL 5; F2I11.150; F2I11_150; REVERSAL OF THE DET PHENOTYPE 5; TED 5
NCBI Protein Information
Basic-leucine zipper (bZIP) transcription factor family protein
NCBI Summary
Basic leucine zipper (bZIP) transcription factor. Nuclear localization. Involved in light-regulated transcriptional activation of G-box-containing promoters. Negatively regulated by Cop1. Although cytokinins do not appear to affect the gene's promoter activity, they appear to stabilize the protein. HY5 plays a role in anthocyanin accumulation in far-red light and blue light, but not in red light or in the dark. Mutant studies showed that the gene product is involved in the positive regulation of the PHYA-mediated inhibition of hypocotyl elongation. Binds to G- and Z-boxes, and other ACEs, but not to E-box. Loss of function mutation shows ABA resistant seedling phenotypes suggesting involvement for HY5 in mediating ABA responses. Binds to the promoter of ABI5 and regulates its expression.
UniProt Gene Name
HY5
UniProt Synonym Gene Names
BZIP56; AtbZIP56
UniProt Protein Name
Transcription factor HY5
UniProt Synonym Protein Names
Protein LONG HYPOCOTYL 5; bZIP transcription factor 56; AtbZIP56
UniProt Primary Accession #
O24646
UniProt Related Accession #
O24646
UniProt Comments
Transcription factor that promotes photomorphogenesis in light. Acts downstream of the light receptor network and directly affects transcription of light-induced genes. Specifically involved in the blue light specific pathway, suggesting that it participates in transmission of cryptochromes (CRY1 and CRY2) signals to downstream responses. In darkness, its degradation prevents the activation of light-induced genes (Probable). Acts coordinately with SPL7 to regulate the microRNA miR408 and its target genes in response to changes in light and copper conditions (PubMed:25516599). Regulates the abscisic acid (ABA) signaling pathway. Also involved in root gravitropism (PubMed:26474641).
For research use only, not for clinical use.