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Transcription factor E2FB (E2FB), Recombinant Protein
Cat: RP01143
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Transcription factor E2FB (E2FB)
Product Gene Name
E2FB recombinant protein
Product Synonym Gene Name
E2FB
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MSEEVPQQFP SSKRQLHPSL SSMKPPLVAP GEYHRFDAAE TRGGGAVADQ VVSDAIVIKS TLKRKTDLVN QIVEVNELNT GVLQTPVSGK GGKAKKTSRS AKSNKSGTLA SGSNAGSPGN NFAQAGTCRY DSSLGLLTKK FINLIKQAED GILDLNKAAD TLEVQKRRIY DITNVLEGIG LIEKTLKNRI QWKGLDVSKP GETIESIANL QDEVQNLAAE EARLDDQIRE SQERLTSLSE DENNKRLLFV TENDIKNLPC FQNKTLIAVK APHGTTLEVP DPDEAGGYQR RYRIILRSTM GPIDVYLVSQ FEESFEDIPQ ADEPSNVPDE PSNVPDVPSN LPSTSGLPEN HDVSMPMKEE STERNMETQE VDDTQRVYSD IESHDFVDGI MKIVPPDLDM GVDYWFRSEV GEVSITDMWP DESGPDWNQM ITFDQDHAGP SDNKILEQPQ TPSSPTPEES TATRSPTGS
Sequence Positions
1-469, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
51,460 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Transcription factor
NCBI/Uniprot Data
NCBI Accession #
NP_001031921.3
NCBI GI #
186524814
NCBI GenBank Nucleotide #
NM_001036844.3
NCBI GeneID
832283
NCBI Official Full Name
E2F transcription factor 1
NCBI Official Symbol
E2F1
NCBI Official Synonym Symbols
ATE2FB; E2F transcription factor 1; E2F TRANSCRIPTION FACTOR-1 E2F1; E2FB; E2FB TRANSCRIPTION FACTOR
NCBI Protein Information
E2F transcription factor 1
NCBI Summary
Member of the E2F transcription factors, (cell cycle genes), key components of the cyclin D/retinoblastoma/E2F pathway. Binds DPA and RBR1 proteins. Expressed throughout the cell cycle. Abundance increased by auxin through stabilization of the protein. Elevates CDK levels and activity, even under hormone-free conditions. Promotes cell division and shortens cell doubling time, inhibits cell growth. Transgenic plants overexpressing AtE2Fa contained an increased level of AtE2Fb transcripts that is paralleled by an increase in the amount of the AtE2Fb protein, suggesting that AtE2Fb expression might actually be up-regulated by the AtE2Fa transcription factor.
UniProt Gene Name
E2FB
UniProt Synonym Gene Names
E2F1; AtE2F1
UniProt Protein Name
Transcription factor E2FB
UniProt Synonym Protein Names
E2F transcription factor-1; AtE2F1
UniProt Primary Accession #
Q9FV71
UniProt Secondary Accession #
Q9FMS8; Q9FNY1
UniProt Related Accession #
Q9FV71
UniProt Comments
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions.
For research use only, not for clinical use.