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TOR, Recombinant Protein
Cat: RP00757
Size: 0.05 mg/ 0.1 mg/ 5x0.1 mg
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Mouse-ear cress TOR protein, N-His Tag
Product Synonym Names
Serinethreonine-protein kinase TOR AtTOR Protein TARGET OF RAPAMYCIN TOR
Product Gene Name
TOR recombinant protein
Purity
>90% as determined by SDS-PAGE
Format
Lyophilized. Lyophilized from PBS pH 7.4, 0.2% NLS, 5% Trehalose, 5% Mannose, 1mM EDTA.
Host
E Coli
Molecular Weight
279,190 Da
Storage
Store at 2 to 8℃ for one week. Store at -20 to -80℃ for twelve months from the date of receipt. Use a manual defrost freezer and avoid repeated freeze thaw cycles.In general, proteins are provided as lyophilized powder or frozen liquid. They are shipped out with dry ice or blue ice unless customers require otherwise.
Protein Family
Torsin
NCBI/Uniprot Data
NCBI Accession #
NP_175425.2
NCBI GI #
22330143
NCBI GenBank Nucleotide #
NM_103891.4
NCBI GeneID
841427
NCBI Official Full Name
target of rapamycin
NCBI Official Symbol
TOR
NCBI Official Synonym Symbols
F2J10.19; F2J10_19; target of rapamycin
NCBI Protein Information
target of rapamycin
NCBI Summary
Related to TOR proteins from yeast and mammals, regulators of cell growth in response to nutrient availability. TOR proteins belong to the family of phosphatidylinositol 3-kinase and are targets of the antiproliferative drug rapamycin. AtTOR binds the yeast FKBP12 protein in the presence of Rapamycin, is involved in embryogenesis and is expressed in embryos, endosperm and meristems.
UniProt Gene Name
TOR
UniProt Synonym Gene Names
AtTOR
UniProt Protein Name
Serine/threonine-protein kinase TOR
UniProt Synonym Protein Names
Protein TARGET OF RAPAMYCIN
UniProt Primary Accession #
Q9FR53
UniProt Secondary Accession #
Q9LPM4
UniProt Related Accession #
Q9FR53
UniProt Comments
Essential cell growth regulator that controls development from early embryo to seed production. Controls plant growth in environmental stress conditions. Acts through the phosphorylation of downstream effectors that are recruited by the binding partner RAPTOR. Acts by activating transcription, protein synthesis and ribosome biogenesis, and inhibiting mRNA degradation and autophagy. Can phosphorylate TAP46, a regulatory subunit of protein phosphatase 2A that modulates cell growth and survival (PubMed:21216945). Involved in modulating the transition from heterotrophic to photoautotrophic growth by regulating the expression of chloroplast- and photosynthesis-associated genes (PubMed:27479935). Essential for auxin signaling transduction, probably acting in polysomes to maintain the active ATPK1/S6K1 (and thus TIF3H1/eIF3h) phosphorylation status that is critical for translation reinitiation (e.g. uORF-mRNAs loading) (PubMed:23524850, PubMed:27014314). Promotes abscisic acid (ABA) biosynthesis (PubMed:26459592). Involved in the regulation of sugar-mediated (e.g. glucose and sucrose) glycolysis- and mitochondrial bioenergetics-dependent root growth promotion (PubMed:23542588). Required for sugar (e.g. glucose) promotion of hypocotyl elongation in the dark, by activating the brassinosteroid pathway and stabilizing BZR1. The regulation of BZR1 degradation is dependent on autophagy (PubMed:27345161).
For research use only, not for clinical use.