Products
Online Inquiry
Thiamine thiazole synthase 2, chloroplastic (THI1-2), Recombinant Protein
Cat: RP18912
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Vitis vinifera (Grape)
Datasheet:
Product Info
Full Product Name
Recombinant Vitis vinifera Thiamine thiazole synthase 2, chloroplastic (THI1-2)
Product Gene Name
THI1-2 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
EMTRRYMMDM ITYADTDVVI VGAGSAGLSC AYELSKNPSI RVAIIEQSVS PGGGAWLGGQ LFSAMVVRKP AHHFLDELGI EYDEQDNYVV IKHAALFTST IMSKLLARPN VKLFNAVAAE DLIVKEERVA GVVTNWALVS MNHDTQSCMD PNVMEAKVVV SSCGHDGPFG ATGVKRLKSI GMIDSVPGMK ALDMNTAEDA IVRLTREIVP GMIVTGMEVA EIDGAPRMGP TFGAMMISGQ KAAHLALRAL GQPNAIDGNY TEAETMQPEL ILAAAETGEI VDA
Sequence Positions
73-355, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
38,105 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Thiamine thiazole synthase
NCBI/Uniprot Data
NCBI Accession #
XP_002267414.1
NCBI GI #
225444377
NCBI GenBank Nucleotide #
XM_002267378.4
NCBI GeneID
100265774
NCBI Official Full Name
thiamine thiazole synthase 2, chloroplastic
NCBI Official Symbol
THI1-2
NCBI Protein Information
thiamine thiazole synthase 2, chloroplastic
UniProt Gene Name
THI1-2
UniProt Protein Name
Thiamine thiazole synthase 2, chloroplastic
UniProt Synonym Protein Names
Thiazole biosynthetic enzyme 2
UniProt Primary Accession #
F6H7K5
UniProt Related Accession #
F6H7K5
UniProt Comments
Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
For research use only, not for clinical use.