Thiamine thiazole synthase 1, chloroplastic (THI1-1), Recombinant Protein

Cat: RP18915

Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)

Species: Vitis vinifera (Grape)

Datasheet:

Product Info

Full Product Name

Recombinant Vitis vinifera Thiamine thiazole synthase 1, chloroplastic (THI1-1)

Product Gene Name

THI1-1 recombinant protein

Purity

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Sequence

AAAMPYDLRS FKFEPIKESI VSREMTRRYM MDMITYADTD VVVVGAGSAG LSCAYELSKN PSVQVAIIEQ SVSPGGGAWL GGQLFSSMVV RKPAHRFLDE LGLEYDEQDN YVVIKHAALF TSTIMSKLLA RPNVKLFNAV AAEDLIIKEG KVGGVVTNWA LVSMNHDTQS CMDPNVMEAK VVVSSCGHDG PFGATGVKRL RSVGMIDSVP GMKALDMNTA EDEIVRLTRE VVPGMIVTGM EVAEIDGSPR MGPTFGAMMI SGQKAAHLAL KSLGLPNALD GTYIGNLHPE LVLAAAADAA EIAEA

Sequence Positions

49-353, Full length protein

Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Molecular Weight

37,513 Da

Storage

Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

Protein Family

Thiamine thiazole synthase

NCBI/Uniprot Data

NCBI Accession #

XP_002281769.1

NCBI GI #

225461077

NCBI GenBank Nucleotide #

XM_002281733.3

NCBI GeneID

100260728

NCBI Official Full Name

thiamine thiazole synthase 1, chloroplastic

NCBI Official Symbol

THI1-1

NCBI Protein Information

thiamine thiazole synthase 1, chloroplastic

UniProt Gene Name

THI1-1

UniProt Protein Name

Thiamine thiazole synthase 1, chloroplastic

UniProt Synonym Protein Names

Thiazole biosynthetic enzyme 1

UniProt Primary Accession #

F6H9A9

UniProt Related Accession #

F6H9A9

UniProt Comments

Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.

For research use only, not for clinical use.