Telomerase reverse transcriptase (TERT), Recombinant Protein
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Telomerase reverse transcriptase (TERT), Recombinant Protein

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Cat: RP01799
Size: 0.05 mg (E-Coli)/ 0.05 mg (Yeast)/ 0.2 mg (E-Coli)/ 0.05 mg (Baculovirus)/ 0.5 mg (E-Coli)/ 0.2 mg (Yeast)/ 0.05 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 0.5 mg (Yeast)/ 1 mg (E-Coli)/ 0.5 mg (Baculovirus)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (B
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Telomerase reverse transcriptase (TERT) , partial
Product Gene Name
TERT recombinant protein
Product Synonym Gene Name
TERT
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
LVDDAEAESS RKKLSKFRFL PKANGVRMVL DFSSSSRSQS LRDTHAVLKD IQLKEPDVLG SSVFDHDDFY RNLCPYLIHL RSQSGELPPL YFVVADVFKA FDSVDQGKLL HVIQSFLKDE YILNRCRLVC CGKRSNWVNK ILVSSDKNSN FSRFTSTVPY NALQSIVVDK GENHRVRKKD LMVWIGNMLK NNMLQLDKSF YVQIAGIPQG HRLSSLLCCF YYGHLERTLI YPFLEEASKD VSSKECSREE ELIIPTSYKL LRFIDDYLFV STSRDQASSF YHRLKHGFKD YNCFMNETKF CINFEDKEEH RCSSNRMFVG DNGVPFVRWT GLLI
Sequence Positions
596-929. Partial, provide the Reverse transcriptase Domain
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
130,580 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Telomerase reverse transcriptase

NCBI/Uniprot Data

NCBI Accession #
NP_197187.1
NCBI GI #
15237420
NCBI GenBank Nucleotide #
NM_121691.4
NCBI GeneID
831548
NCBI Official Full Name
telomerase reverse transcriptase
NCBI Official Symbol
TERT
NCBI Official Synonym Symbols
ATTERT; F5E19.190; F5E19_190; telomerase reverse transcriptase
NCBI Protein Information
telomerase reverse transcriptase
NCBI Summary
Encodes the catalytic subunit of telomerase reverse transcriptase. Involved in telomere homeostasis. Homozygous double mutants with ATR show gross morphological defects over a period of generations. TERT shows Class II telomerase activity in vitro, indicating that it can initiate de novo telomerase synthesis on non-telomeric DNA, often using a preferred position within the telomerase-bound RNA.
UniProt Gene Name
TERT
UniProt Synonym Gene Names
AtTERT
UniProt Protein Name
Telomerase reverse transcriptase
UniProt Primary Accession #
Q9SPU7
UniProt Secondary Accession #
Q9SE99
UniProt Related Accession #
Q9SPU7
UniProt Comments
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Required to prevent genome instability induced by breakage-fusion-bridge (BFB) cycles. Can extend completely non-telomeric sequences using RNA template in vitro.

For research use only, not for clinical use.