NCBI Accession #
NP_001234574.1
NCBI GenBank Nucleotide #
NM_001247645.2
NCBI Official Full Name
succinate--CoA ligase
NCBI Official Symbol
LOC543943
NCBI Protein Information
succinate--CoA ligase [ADP-forming] subunit alpha-2, mitochondrial
UniProt Gene Name
SCS-alpha-2
UniProt Synonym Gene Names
SCS-alpha-2
UniProt Protein Name
Succinate--CoA ligase [ADP-forming] subunit alpha-2, mitochondrial
UniProt Synonym Protein Names
Succinyl-CoA synthetase subunit alpha-2
UniProt Primary Accession #
Q6DQL1
UniProt Related Accession #
Q6DQL1
UniProt Comments
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.