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Squalene monooxygenase 1,2 (SQP1,2) (SQE6), Recombinant Protein
Cat: RP00310
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Squalene monooxygenase 1,2 (SQP1,2)
Product Synonym Names
Recombinant Squalene monooxygenase 1,2 (SQP1,2); Squalene monooxygenase 1,2 EC= 1.14.13.132; Squalene epoxidase 1,2; SE 1,2
Product Gene Name
SQE6 recombinant protein
Product Synonym Gene Name
SQP1,2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MAFTHVCLWT LVAFVLTWTV FYLTNMKKKA TDLADTVAED QKDGAADVII VGAGVGGSAL AYALAKDGRR VHVIERDMRE PERMMGEFMQ PGGRLMLSKL GLQDCLEDID AQKATGLAVY KDGKEADAPF PVDNNNFSYE PSARSFHNGR FVQQLRRKAF SLSNVRLEEG TVKSLLEEKG VVKGVTYKNK EGEETTALAP LTVVCDGCYS NLRRSLNDDN NAEIMSYIVG YISKNCRLEE PEKLHLILSK PSFTMVYQIS STDVRCGFEV LPENFPSIAN GEMSTFMKNT IVPQVPPKLR KIFLKGIDEG AHIKVVPAKR MTSTLSKKKG VIVLGDAFNM RHPVVASGMM VLLSDILILR RLLQPLSNLG DANKVSEVIN SFYDIRKPMS ATVNTLGNAF SQVLIGSTDE AKEAMRQGVY DYLCSGGFRT SGMMALLGGM NPRPLSLVYH LCAITLSSIG QLLSPFPSPL RIWHSLKLFG LAMKMLVPNL KAEGVSQMLF PANAAAYHKS YMAATTL
Sequence Positions
1-517
Chromosome Location
Chromosome: 5; NC_003076.8 (8183075..8186640, complement). Location: chromosome: 5
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
56,890 Da
Storage
Store at -20℃. For extended storage, store at -20 or -80℃.
Protein Family
Squalene epoxidase
NCBI/Uniprot Data
NCBI Accession #
NP_197804.1
NCBI GI #
15237903
NCBI GenBank Nucleotide #
NM_122321.4
NCBI GeneID
832482
NCBI Official Full Name
Squalene monooxygenase 1,2
NCBI Official Symbol
SQE6
NCBI Official Synonym Symbols
K12G2.4; K12G2_4; SQE6; squalene monoxygenase 6
NCBI Protein Information
Squalene monooxygenase 1,2
UniProt Gene Name
SQP1,2
UniProt Synonym Gene Names
SE 1,2
UniProt Protein Name
Squalene monooxygenase 1,2
UniProt Synonym Protein Names
Squalene epoxidase 1,2
UniProt Entry Name
ERG12_ARATH
UniProt Primary Accession #
O65402
UniProt Related Accession #
T51363
UniProt Comments
Function: Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway.Catalytic activity: Squalene + NADPH + O2 = (3S)-2,3-epoxy-2,3-dihydrosqualene + NADP+ + H2O.Cofactor: FAD.Pathway: Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 2/3.Subcellular location: Membrane; Multi-pass membrane protein Potential. Sequence similarities: Belongs to the squalene monooxygenase family.
For research use only, not for clinical use.