Shaggy-related protein kinase eta (ASK7), Recombinant Protein
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Shaggy-related protein kinase eta (ASK7), Recombinant Protein

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Cat: RP01768
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Shaggy-related protein kinase eta (ASK7)
Product Gene Name
ASK7 recombinant protein
Product Synonym Gene Name
ASK7
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MADDKEMPAA VVDGHDQVTG HIISTTIGGK NGEPKQTISY MAERVVGTGS FGIVFQAKCL ETGETVAIKK VLQDRRYKNR ELQLMRVMDH PNVVCLKHCF FSTTSKDELF LNLVMEYVPE SLYRVLKHYS SANQRMPLVY VKLYMYQIFR GLAYIHNVAG VCHRDLKPQN LLVDPLTHQV KICDFGSAKQ LVKGEANISY ICSRFYRAPE LIFGATEYTT SIDIWSAGCV LAELLLGQPL FPGENAVDQL VEIIKVLGTP TREEIRCMNP HYTDFRFPQI KAHPWHKIFH KRMPPEAIDF ASRLLQYSPS LRCTALEACA HPFFDELREP NARLPNGRPF PPLFNFKQEV AGSSPELVNK LIPDHIKRQL GLSFLNQSGT
Sequence Positions
1-380, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
43,099 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
SKP1-like protein

NCBI/Uniprot Data

NCBI Accession #
NP_193606.1
NCBI GI #
15233984
NCBI GenBank Nucleotide #
NM_117987.4
NCBI GeneID
827605
NCBI Official Full Name
Protein kinase superfamily protein
NCBI Official Symbol
BIN2
NCBI Official Synonym Symbols
ATSK21; BRASSINOSTEROID-INSENSITIVE 2; DWARF 12; DWF12; F28A21.120; F28A21_120; SHAGGY-LIKE KINASE 21; SK21; UCU1; ULTRACURVATA 1
NCBI Protein Information
Protein kinase superfamily protein
NCBI Summary
Encodes BIN2, a member of the ATSK (shaggy-like kinase) family. BIN2 functions in the cross-talk between auxin and brassinosteroid signaling pathways. BIN2 regulates root epidermal cell fate specification by phosphorylating EGL3 and TTG1. BIN2-mediated phosphorylation appears to promote BZR1 export from the nucleus.
UniProt Gene Name
ASK7
UniProt Synonym Gene Names
AtSK21
UniProt Protein Name
Shaggy-related protein kinase eta
UniProt Synonym Protein Names
ASK-eta
UniProt Primary Accession #
Q39011
UniProt Secondary Accession #
Q147R2; Q8S9H8; Q9SN42
UniProt Related Accession #
Q39011
UniProt Comments
Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5 (PubMed:11847343, PubMed:12114546, PubMed:12427989, PubMed:17280695, PubMed:22307275, PubMed:23341468). Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in vitro (PubMed:23496207).

For research use only, not for clinical use.