NCBI Accession #
NP_182073.1
NCBI GenBank Nucleotide #
NM_130111.4
NCBI Official Full Name
ataurora3
NCBI Official Symbol
AUR3
NCBI Official Synonym Symbols
AtAUR3; ataurora3; F17K2.2
NCBI Protein Information
ataurora3
NCBI Summary
Encodes a member of a family of Ser/Thr kinases whose activities peak during cell division. Transcripts are abundant in tissues rich in dividing cells like roots and flowers but are low or absent in fully expanded leaves and stems. In interphase cells, the protein is predominantly nuclear. During mitosis, the protein associates with plant-specific cytoskeletal structures (preprophase band, phragmoplast, nascent cell plate) that are necessary for cytokinesis as well as with the microtubule spindle. The protein is concentrated in nuclear dots arranged around the nucleolus and the nuclear periphery in early prophase cells.
UniProt Synonym Gene Names
AtAur3
UniProt Protein Name
Serine/threonine-protein kinase Aurora-3
UniProt Synonym Protein Names
Aurora-like kinase 3
UniProt Primary Accession #
O64629
UniProt Related Accession #
O64629
UniProt Comments
Phosphorylates in vitro histone H3 at 'Ser-10' (H3S10ph) and 'Ser-28' (H3S28ph), but not at 'Thr-3' (H3T3ph) or 'Thr-11' (H3T11ph). Colocalizes with phosphorylated histone H3 during mitosis. Associates with cytoskeletal structures that are necessary for cytokinesis and with the microtubule spindle.