NCBI Accession #
NP_201203.3
NCBI GenBank Nucleotide #
NM_125794.5
NCBI Official Full Name
SAL1 phosphatase-like protein
NCBI Official Symbol
SAL1
NCBI Official Synonym Symbols
ALTERED EXPRESSION OF APX2 8; ALX8; AtFRY1; ATSAL1; FIERY1; FRY1; HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 2; HOS2; MBM17.8; MBM17_8; RON1; ROTUNDA 1; SUPO1; suppressors of PIN1 overexpression 1
NCBI Protein Information
SAL1 phosphatase-like protein
NCBI Summary
Encodes a bifunctional protein that has 3'(2'),5'-bisphosphate nucleotidase and inositol polyphosphate 1-phosphatase activities and rescues sulfur assimilation mutants in yeast. It is involved in the response to cold, drought (negative regulator of drought tolerance), and ABA. Mutants in this gene exhibit enhanced induction of stress genes in response to cold, ABA, salt and dehydration due to higher accumulation of the second messenger, inositol (1,4,5)- triphosphate (IP(3)). Involved in degradation of small mRNAs. Mutants also affect the accumulation of miRNA target cleavage products. Regulates light-dependent repression of hypocotyl elongation and flowering time via its 3'(2'),5'-bisphosphate nucleotidase activity.
UniProt Synonym Gene Names
FRY1; IPPase 1
UniProt Protein Name
SAL1 phosphatase
UniProt Synonym Protein Names
3'(2'),5'-bisphosphate nucleotidase 1 (EC:3.1.3.7); 3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase 1; DPNPase 1; Inositol polyphosphate 1-phosphatase 1; IPPase 1; Inositol-1,4-bisphosphate 1-phosphatase 1 (EC:3.1.3.57); Protein FIERY 1
UniProt Primary Accession #
Q42546
UniProt Secondary Accession #
Q0WTT5; F4KC73
UniProt Related Accession #
Q42546
UniProt Comments
Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS. May play a role in the biosynthesis of sulfate conjugates and RNA processing. Is also able to hydrolyze inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate. Could be considered as a negative regulator of abscisic acid (ABA)- and stress-responsive genes, through modulating the inositol 1,4,5-trisphosphate (IP3) turnover. Is also involved in salt tolerance. Acts as a suppressor of virus- and transgene-induced silencing.