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rRNA 2'-O-methyltransferase fibrillarin 1 (FIB1), Recombinant Protein
Cat: RP01081
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 1 mg (E-Coli)/ 5x1 mg (E-Coli)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana rRNA 2'-O-methyltransferase fibrillarin 1 (FIB1)
Product Synonym Names
rRNA 2'-O-methyltransferase fibrillarin 1; EC=2.1.1.-; SKP1-interacting partner 7
Product Gene Name
FIB1 recombinant protein
Product Synonym Gene Name
FIB1; FBR1; SKIP7; At5g52470; K24M7.22
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MRPPVTGGRG GGGFRGGRDG GGRGFGGGRS FGGGRSGDRG RSGPRGRGRG APRGRGGPPR GGMKGGSKVI VEPHRHAGVF IAKGKEDALV TKNLVPGEAV YNEKRISVQN EDGTKVEYRV WNPFRSKLAA AILGGVDNIW IKPGAKVLYL GAASGTTVSH VSDLVGPEGC VYAVEFSHRS GRDLVNMAKK RTNVIPIIED ARHPAKYRML VGMVDVIFSD VAQPDQARIL ALNASFFLKT GGHFVISIKA NCIDSTVAAE AVFQSEVKKL QQEQFKPAEQ VTLEPFERDH ACVVGGYRMP KKQKTPAS
Sequence Positions
1-308aa; Full Length
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
48.8 kDa
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
NCBI/Uniprot Data
NCBI Accession #
NP_001119418.1
NCBI GI #
186531481
NCBI GenBank Nucleotide #
NM_001125946.1
NCBI GeneID
835323
NCBI Official Full Name
probable mediator of RNA polymerase II transcription subunit 36b
NCBI Official Symbol
FIB1
NCBI Official Synonym Symbols
ATFBR1; ATFIB1; FBR1; FIB1; fibrillarin 1; FIBRILLARIN 1; K24M7.22; K24M7_22; SKIP7; SKP1/ASK1-INTERACTING PROTEIN
NCBI Protein Information
probable mediator of RNA polymerase II transcription subunit 36b
UniProt Gene Name
MED36B
UniProt Synonym Gene Names
FBR1; FIB1; MED36_2; SKIP7
UniProt Protein Name
Probable mediator of RNA polymerase II transcription subunit 36b
UniProt Synonym Protein Names
Histone-glutamine methyltransferase; SKP1-interacting partner 7; rRNA 2'-O-methyltransferase fibrillarin 1 (EC:2.1.1.-)
UniProt Entry Name
MD36B_ARATH
UniProt Primary Accession #
Q9FEF8
UniProt Secondary Accession #
Q0WLG3; Q9FUZ8; Q9SP30; B3H6E7
UniProt Related Accession #
Q9FEF8
UniProt Comments
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors .
For research use only, not for clinical use.