RNA-dependent RNA polymerase 2 (RDR2), Recombinant Protein
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RNA-dependent RNA polymerase 2 (RDR2), Recombinant Protein

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Cat: RP02101
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana RNA-dependent RNA polymerase 2 (RDR2) , partial
Product Gene Name
RDR2 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
129,325 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
RNA-dependent RNA polymerase

NCBI/Uniprot Data

NCBI Accession #
NP_192851.1
NCBI GI #
15237051
NCBI GenBank Nucleotide #
NM_117183.3
NCBI GeneID
826714
NCBI Official Full Name
RNA-dependent RNA polymerase 2
NCBI Official Symbol
RDR2
NCBI Official Synonym Symbols
AtRDR2; RNA-dependent RNA polymerase 2; SILENCING MOVEMENT DEFICIENT 1; SMD1; T22B4.110; T22B4_110
NCBI Protein Information
RNA-dependent RNA polymerase 2
NCBI Summary
Encodes RNA-dependent RNA polymerase that is required for endogenous siRNA (but not miRNA) formation. Nomenclature according to Xie, et al. (2004).
UniProt Gene Name
RDR2
UniProt Synonym Gene Names
RDRP2; SMD1; AtRDRP2
UniProt Protein Name
RNA-dependent RNA polymerase 2
UniProt Synonym Protein Names
Protein SILENCING MOVEMENT DEFICIENT 1; RNA-directed RNA polymerase 2
UniProt Primary Accession #
O82504
UniProt Related Accession #
O82504
UniProt Comments
RNA-dependent direct polymerase involved in the production of small interfering RNAs (siRNAs). Required for the biogenesis of endogenous siRNAs of 24 nucleotide which derive from heterochromatin and DNA repeats such as transposons or endogenous gene tandem repeats, such as repeats present in FWA gene. Involved in transcriptional gene silencing (TGS). Component of the RNA-directed DNA methylation (RdDM) silencing pathway that utilizes siRNAs to guide DNA methyltransferases to asymmetric cytosines. Involved in control of flowering time through RdDM of FWA locus. Required for reception of long-distance mRNA silencing in the shoot. Required for the formation of telomeric siRNAs and the RNA-dependent DNA methylation of asymmetric cytosines in telomeric (5'-CCCTAAA-3') repeats.

For research use only, not for clinical use.