RNA-dependent RNA polymerase 1 (RDR1), Recombinant Protein
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RNA-dependent RNA polymerase 1 (RDR1), Recombinant Protein

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Cat: RP01085
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana RNA-dependent RNA polymerase 1 (RDR1) , partial
Product Gene Name
RDR1 recombinant protein
Product Synonym Gene Name
RDR1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
KGLRPHPNEC SGSDLDGDIY FVCWDQELVP PRTSEPMDYT PEPTQILDHD VTIEEVEEYF ANYIVNDSLG IIANAHTAFA DKEPLKAFSD PCIELAKKFS TAVDFPKTGV AAVIPQHLYV KEYPDFMEKP DKPTYESKNV IGKLFREVKE RAPPLISIKS FTLDVASKSY DKDMEVDGFE EYVDEAFYQK ANYDFKLGNL MDYYGIKTEA EILSGGIMRM SKSFTKRRDA ESIGRAVRAL RKETLSLFNA SEEEENESAK ASA
Sequence Positions
784-1046. Partial
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
126,214 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
RNA-dependent RNA polymerase

NCBI/Uniprot Data

NCBI Accession #
NP_172932.1
NCBI GI #
15223906
NCBI GenBank Nucleotide #
NM_101348.4
NCBI GeneID
838044
NCBI Official Full Name
RNA-dependent RNA polymerase 1
NCBI Official Symbol
RDR1
NCBI Official Synonym Symbols
AtRDR1; ATRDRP1; F10B6.19; F10B6_19; RNA-dependent RNA polymerase 1
NCBI Protein Information
RNA-dependent RNA polymerase 1
NCBI Summary
Encodes RNA-dependent RNA polymerase. While not required for virus-induced post-transcriptional gene silencing (PTGS), it can promote turnover of viral RNAs in infected plants. Nomenclature according to Xie, et al. (2004). Involved in the production of Cucumber Mosaic Virus siRNAs.
UniProt Gene Name
RDR1
UniProt Synonym Gene Names
RDRP1; AtRDRP1
UniProt Protein Name
RNA-dependent RNA polymerase 1
UniProt Synonym Protein Names
RNA-directed RNA polymerase 1
UniProt Primary Accession #
Q9LQV2
UniProt Secondary Accession #
Q8H1K9; Q9ZRX5
UniProt Related Accession #
Q9LQV2
UniProt Comments
RNA-dependent direct polymerase involved in antiviral silencing. Required for the production of some small RNAs (mainly 21 and some 22 nucleotides) derived from the crucifer-infecting tobamovirus (TMV-cg). Required for turnip mosaic virus (TuMV) silencing and accumulation of viral siRNAs. Involved in cucumber mosaic virus (CMV) silencing. Required for the biogenesis of viral secondary siRNAs, process that follows the production of primary siRNAs derived from viral RNA replication. Specifically targets the positive-strand of the 3 RNA genomes of CMV and preferentially amplifies the 5'-terminal siRNAs of each viral genomic RNA. Not involved in the production of siRNAs derived from a single-stranded 336-nucleotide satellite RNA of CMV.

For research use only, not for clinical use.