Ricin (LOC8261245), Recombinant Protein
  1. Home
  2. Products
  3. Plant Proteins
  4. Recombinant Plant Proteins
  5. Recombinant Ricinus Communis (Castor Bean) Protein
Products
Online Inquiry

Ricin (LOC8261245), Recombinant Protein

Inquiry
Cat: RP19086
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Ricinus communis (Castor bean)
Datasheet:

Product Info

Full Product Name
Recombinant Ricinus communis Ricin
Product Gene Name
LOC8261245 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
IFPKQYPIIN FTTAGATVQS YTNFIRAVRG RLTTGADVRH EIPVLPNRVG LPINQRFILV ELSNHAELSV TLALDVTNAY VVGYRAGNSA YFFHPDNQED AEAITHLFTD VQNRYTFAFG GNYDRLEQLA GNLRENIELG NGPLEEAISA LYYYSTGGTQ LPTLARSFII CIQMISEAAR FQYIEGEMRT RIRYNRRSAP DPSVITLENS WGRLSTAIQE SNQGAFASPI QLQRRNGSKF SVYDVSILIP IIALMVYRCA PPPSSQF
Sequence Positions
36-302aa; Partial
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
64,091 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Ricin

NCBI/Uniprot Data

NCBI Accession #
NP_001310630.1
NCBI GI #
1021312434
NCBI GenBank Nucleotide #
NM_001323701.1
NCBI GeneID
8261245
NCBI Official Full Name
ricin
NCBI Official Symbol
LOC8261245  
NCBI Protein Information
ricin
UniProt Protein Name
Ricin
UniProt Synonym Protein Names
Ricin A chain (EC:3.2.2.22)Alternative name(s):rRNA N-glycosidase
UniProt Primary Accession #
P02879
UniProt Related Accession #
P02879
UniProt Comments
Ricin is highly toxic to animal cells and to a lesser extent to plant cells. The A chain acts as a glycosidase that removes a specific adenine residue from an exposed loop of the 28S rRNA (A4324 in mammals), leading to rRNA breakage. As this loop is involved in elongation factor binding, modified ribosomes are catalytically inactive and unable to support protein synthesis. The A chain can inactivate a few thousand ribosomes per minute, faster than the cell can make new ones. Therefore a single A chain molecule can kill an animal cell. The B chain binds to beta-D-galactopyranoside moieties on cell surface glycoproteins and glycolipids and facilitates the entry into the cell of the A chain; B chains are also responsible for cell agglutination (Lectin activity).

For research use only, not for clinical use.