Regulator of nonsense transcripts 1 homolog (UPF1), Recombinant Protein
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Regulator of nonsense transcripts 1 homolog (UPF1), Recombinant Protein

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Cat: RP01927
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Regulator of nonsense transcripts 1 homolog (UPF1) , partial
Product Gene Name
UPF1 recombinant protein
Product Synonym Gene Name
UPF1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
136,868 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Regulator of nonsense transcripts

NCBI/Uniprot Data

NCBI Accession #
NP_199512.2
NCBI GI #
30695086
NCBI GenBank Nucleotide #
NM_124072.3
NCBI GeneID
834747
NCBI Official Full Name
RNA helicase
NCBI Official Symbol
LBA1
NCBI Official Synonym Symbols
ATUPF1; LOW-LEVEL BETA-AMYLASE 1; MQD22.15; MQD22_15; UPF1
NCBI Protein Information
RNA helicase
NCBI Summary
Required for nonsense-mediated mRNA decay. Involved in RNA interference. lba1 mutants has reduced sugar-induced expression of Atb- amylase, is hypersensitive to glucose and abscisic acid and resistant to mannose, and shows early flowering, short day-sensitive growth, and seed germination phenotypes.
UniProt Gene Name
UPF1
UniProt Synonym Gene Names
LBA1
UniProt Protein Name
Regulator of nonsense transcripts 1 homolog
UniProt Synonym Protein Names
ATP-dependent helicase UPF1
UniProt Primary Accession #
Q9FJR0
UniProt Secondary Accession #
Q8S3K7
UniProt Related Accession #
Q9FJR0
UniProt Comments
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (premature termination codon PTC) by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Eliminates the production of nonsense-containing RNAs (ncRNAs). Required for plant development and adaptation to environmental stresses, including plant defense and response to wounding.

For research use only, not for clinical use.