Pyruvate dehydrogenase E1 component subunit alpha-2, mitochondrial (IAR4), Recombinant Protein
  1. Home
  2. Products
  3. Plant Proteins
  4. Recombinant Plant Proteins
  5. Recombinant Arabidopsis Thaliana Protein
Products
Online Inquiry

Pyruvate dehydrogenase E1 component subunit alpha-2, mitochondrial (IAR4), Recombinant Protein

Inquiry
Cat: RP01740
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Pyruvate dehydrogenase E1 component subunit alpha-2, mitochondrial (IAR4)
Product Gene Name
IAR4 recombinant protein
Product Synonym Gene Name
IAR4
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
VSTDSSPITI ETAVPFTSHL CESPSRSVET SSEEILAFFR DMARMRRMEI AADSLYKAKL IRGFCHLYDG QEALAVGMEA AITKKDAIIT SYRDHCTFIG RGGKLVDAFS ELMGRKTGCS HGKGGSMHFY KKDASFYGGH GIVGAQIPLG CGLAFAQKYN KDEAVTFALY GDGAANQGQL FEALNISALW DLPAILVCEN NHYGMGTATW RSAKSPAYFK RGDYVPGLKV DGMDALAVKQ ACKFAKEHAL KNGPIILEMD TYRYHGHSMS DPGSTYRTRD EISGVRQVRD PIERVRKLLL THDIATEKEL KDMEKEIRKE VDDAVAQAKE SPIPDASELF TNMYVKDCGV ESFGADRKEL KVTLP
Sequence Positions
29-393, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
43,359 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

NCBI/Uniprot Data

NCBI Accession #
NP_173828.1
NCBI GI #
15221692
NCBI GenBank Nucleotide #
NM_102264.5
NCBI GeneID
839031
NCBI Official Full Name
Thiamin diphosphate-binding fold (THDP-binding) superfamily protein
NCBI Official Symbol
IAR4
NCBI Official Synonym Symbols
F3I6.11; F3I6_11; IAA-CONJUGATE-RESISTANT 4
NCBI Protein Information
Thiamin diphosphate-binding fold (THDP-binding) superfamily protein
NCBI Summary
Arabidopsis thaliana pyruvate dehydrogenase E1a-like subunit. 81% identical to a previously characterized Arabidopsis mitochondrial PDH E1a-subunit, At1g59900. Serine 296 phosphorylation of IAR4 has critical function in root hair formation and root development. Changing Ser296 in IAR4 to Ala resulted in a phenotype intermediate between mutant and wild-type, while substitution to Asp was either lethal or caused an extreme dwarf phenotype.
UniProt Gene Name
IAR4
UniProt Synonym Gene Names
PDHE1-A
UniProt Protein Name
Pyruvate dehydrogenase E1 component subunit alpha-2, mitochondrial
UniProt Synonym Protein Names
Protein IAA-CONJUGATE-RESISTANT 4
UniProt Primary Accession #
Q8H1Y0
UniProt Secondary Accession #
O48685
UniProt Related Accession #
Q8H1Y0
UniProt Comments
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

For research use only, not for clinical use.