Products
Online Inquiry
Protein VERNALIZATION INSENSITIVE 3 (VIN3), Recombinant Protein
Cat: RP01637
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Protein VERNALIZATION INSENSITIVE 3 (VIN3) , partial
Product Gene Name
VIN3 recombinant protein
Product Synonym Gene Name
VIN3
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
69,347 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Protein VERNALIZATION INSENSITIVE
NCBI/Uniprot Data
NCBI Accession #
NP_001332646.1
NCBI GI #
1063741813
NCBI GenBank Nucleotide #
NM_001345260.1
NCBI GeneID
835844
NCBI Official Full Name
Fibronectin type III domain-containing protein
NCBI Official Symbol
VIN3
NCBI Official Synonym Symbols
MSF19.4; MSF19_4; VERNALIZATION INSENSITIVE 3
NCBI Protein Information
Fibronectin type III domain-containing protein
NCBI Summary
Encodes a plant homeodomain protein VERNALIZATION INSENSITIVE 3 (VIN3). In planta VIN3 and VRN2, VERNALIZATION 2, are part of a large protein complex that can include the polycomb group (PcG) proteins FERTILIZATION INDEPENDENT ENDOSPERM (FIE), CURLY LEAF (CLF), and SWINGER (SWN or EZA1). The complex has a role in establishing FLC (FLOWERING LOCUS C) repression during vernalization.
UniProt Gene Name
VIN3
UniProt Protein Name
Protein VERNALIZATION INSENSITIVE 3
UniProt Primary Accession #
Q9FIE3
UniProt Secondary Accession #
Q53YX0
UniProt Related Accession #
Q9FIE3
UniProt Comments
Plays a central role in vernalization by mediating the initial transcriptional repression of the homeotic gene FLC, a floral repressor, after a cold treatment. However, due to its transient expression, it cannot maintain repression of FLC, which is then maintained by Polycomb Group complexes containing VRN2 throughout development. Required to deacetylate histones on the FLC promoter. Together with VIL1, required during vernalization for the modifications of FLC and FLM chromatin that are associated with an epigenetically silenced state (e.g. chromatin modifications, histone deacetylation, and trimethylated H3 'Lys-4' H3K4me3 and 'Lys-27' H3K27me3) and with acquisition of competence to flower.
For research use only, not for clinical use.