NCBI Accession #
NP_178125.1
NCBI GenBank Nucleotide #
NM_106657.3
NCBI Official Full Name
Leucine-rich repeat (LRR) family protein
NCBI Official Synonym Symbols
AtRLP17; F18B13.16; F18B13_16; Receptor Like Protein 17; TOO MANY MOUTHS
NCBI Protein Information
Leucine-rich repeat (LRR) family protein
NCBI Summary
Encodes a transmembrane leucine-repeat containing receptor-like protein that is expressed in proliferative postprotodermal cells. Recessive mutation leads to disruption of asymmetric cell division during stomata development. Its transcript levels change after inducing MUTE expression in a mute background.
UniProt Synonym Gene Names
AtRLP17
UniProt Protein Name
Protein TOO MANY MOUTHS
UniProt Synonym Protein Names
Receptor-like protein 17
UniProt Primary Accession #
Q9SSD1
UniProt Secondary Accession #
Q8GWY1
UniProt Related Accession #
Q9SSD1
UniProt Comments
Promotes cell fate progression in stomatal development. In leaves, needed to correctly orient spacing divisions, to limit the number of asymmetric divisions in neighbor cells, and to promote the asymmetric (amplifying) divisions of meristemoids. In stems, promotes the conversion of meristemoids into guard mother cells (GMC) (PubMed:11090210, PubMed:12040198, PubMed:18979118). Positively regulates CAPRICE (CPC) expression in differentiating stomaless-forming cell files (PubMed:19513241). Forms constitutive complexes with ERECTA and ERL1 involved in the recognition of the stomatal regulatory peptides EPF1, EPF2 and EPFL9/STOMAGEN (PubMed:28536146). Modulates the activity of the ligand-receptor pairs EPF2-ERECTA and EPF1-ERL1 in stomatal development (PubMed:16002616, PubMed:22241782). Functions in a combinatorial specific manner with the ERECTA-family (ERf) receptor kinases in the regulation of the immune response (PubMed:27446127).