NCBI Accession #
NP_566705.1
NCBI GenBank Nucleotide #
NM_113136.4
NCBI Official Full Name
time for coffee
NCBI Official Synonym Symbols
TIME FOR COFFEE
NCBI Protein Information
time for coffee
NCBI Summary
Encodes a nucleus-acting plant-specific clock regulator working close to the central oscillator and affecting the circadian gating of light responses. Circadian gating is the alteration of circadian phase according to the photoperiod of the entraining day/light cycle and the rhythmic antagonism of light responses in the early subjective night. TIC differentially regulates CCA1 and PRR9 from LHY, with LHY expression as a dominant genetic target of TIC action. Also shown to be invoved in the maintenance of Arabidopsis thaliana metabolic homeostasis.
UniProt Protein Name
Protein TIME FOR COFFEE
UniProt Primary Accession #
Q94KE2
UniProt Secondary Accession #
Q94C89; Q9LUW1
UniProt Related Accession #
Q94KE2
UniProt Comments
Regulator of normal clock function. Acts in the mid to late night. Contributes to the amplitude of circadian clocks. May act on the transcriptional induction of LATE ELONGATED HYPOCOTYL (LHY). Inhibits MYC2 protein accumulation, acting as a negative factor in the JA-signaling pathway.