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Protein SUPPRESSOR OF PHYA-105 1 (SPA1), Recombinant Protein
Cat: RP02091
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Protein SUPPRESSOR OF PHYA-105 1 (SPA1) , partial
Product Gene Name
SPA1 recombinant protein
Product Synonym Gene Name
SPA1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
114,686 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Protein SUPPRESSOR OF PHYA-105
NCBI/Uniprot Data
NCBI Accession #
NP_001325255.1
NCBI GI #
1063706975
NCBI GenBank Nucleotide #
NM_001337186.1
NCBI GeneID
819242
NCBI Official Full Name
SPA (suppressor of phyA-105) protein family
NCBI Official Symbol
SPA1
NCBI Official Synonym Symbols
AT2G46350; F11C10.3; SUPPRESSOR OF PHYA-105 1
NCBI Protein Information
SPA (suppressor of phyA-105) protein family
NCBI Summary
Encodes a member of the SPA (suppressor of phyA-105) protein family (SPA1-SPA4). SPA proteins contain an N-terminal serine/threonine kinase-like motif followed by a coiled-coil structure and a C-terminal WD-repeat domain. SPA1 is a PHYA signaling intermediate, putative regulator of PHYA signaling pathway. Light responsive repressor of photomorphogenesis. Involved in regulating circadian rhythms and flowering time in plants. Under constant light, the abundance of SPA1 protein exhibited circadian regulation, whereas under constant darkness, SPA1 protein levels remained unchanged. In addition, the spa1-3 mutation slightly shortened circadian period of CCA1, TOC1/PRR1 and SPA1 transcript accumulation under constant light.
UniProt Gene Name
SPA1
UniProt Protein Name
Protein SUPPRESSOR OF PHYA-105 1
UniProt Primary Accession #
Q9SYX2
UniProt Secondary Accession #
Q0WUH3; Q56WP1; Q9SKE4; Q9SKE5
UniProt Related Accession #
Q9SYX2
UniProt Comments
Controls normal photoperiodic flowering and regulates circadian rhythms. Required for suppression of photomorphogenesis in dark-grown seedlings and for normal elongation growth of adult plants. Integral component of the COP1/SPA E3 ubiquitin-protein ligase complex. Involved in HY5, HFR1, LAF1 and CO degradation.
For research use only, not for clinical use.