NCBI Accession #
NP_194338.1
NCBI GenBank Nucleotide #
NM_118741.3
NCBI Official Full Name
Protein phosphatase 2C family protein
NCBI Official Symbol
ABI1
NCBI Official Synonym Symbols
ABA INSENSITIVE 1; AtABI1; F20B18.190; F20B18_190; PROTEIN PHOSPHATASE 2C ABI1
NCBI Protein Information
Protein phosphatase 2C family protein
NCBI Summary
Involved in abscisic acid (ABA) signal transduction. Negative regulator of ABA promotion of stomatal closure.
UniProt Synonym Gene Names
AtPP2C56; PP2C ABI1
UniProt Protein Name
Protein phosphatase 2C 56
UniProt Synonym Protein Names
Protein ABSCISIC ACID-INSENSITIVE 1; Protein phosphatase 2C ABI1; PP2C ABI1
UniProt Primary Accession #
P49597
UniProt Secondary Accession #
Q0WW30; Q43717; Q94C87
UniProt Related Accession #
P49597
UniProt Comments
Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, osmotic water permeability of the plasma membrane (Pos), drought-induced resistance and rhizogenesis, response to glucose, high light stress, seed germination and inhibition of vegetative growth. During the stomatal closure regulation, modulates the inward calcium-channel permeability as well as the actin reorganization in guard cells in response to ABA. Involved in the resistance to the bacterial pathogen Pseudomonas syringae pv. tomato. Controls negatively fibrillin expression that is involved in mediating ABA-induced photoprotection. May be involved in ABA content regulation. Plays a role in the Pro accumulation in response to reduced water availability (low water potential). Required for the ABA negative regulation of the ethylene-induced hyponastic growth. Involved in acquired thermotolerance of root growth and seedling survival. Activates/represses SRK2E/OST1 in response to ABA-dependent stimuli, especially in stomata closure regulation involving SLAC1. Represses MAPKKK18 activity and promotes MAPKKK18 degradation by the proteasome pathway upon abscisic acid (ABA) treatment (PubMed:26443375).