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Protein HOTHEAD (HTH), Recombinant Protein
Cat: RP00221
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Protein HOTHEAD (HTH) , partial
Product Gene Name
HTH recombinant protein
Product Synonym Gene Name
HTH
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
65,344 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Protein
NCBI/Uniprot Data
NCBI Accession #
NP_565050.1
NCBI GI #
18410230
NCBI GenBank Nucleotide #
NM_105955.4
NCBI GeneID
843628
NCBI Official Full Name
Glucose-methanol-choline (GMC) oxidoreductase family protein
NCBI Official Symbol
HTH
NCBI Official Synonym Symbols
ACE; EDA17; embryo sac development arrest 17; F3N23.17; F3N23_17; HOTHEAD
NCBI Protein Information
Glucose-methanol-choline (GMC) oxidoreductase family protein
NCBI Summary
Originally identified as a mutation that causes floral organs to fuse together. About 10-20% of mutants also have defects in ovules. Mutants have reduced fertility most likely as because of fusions that pistil emergence. The protein has similarity to the mandelonitrile lyase family of FAD containing oxidoreductases and is predicted to be secreted (SignalP).It is expressed in all tissue layers of roots, inflorescences, stems, leaves, and flowers and is also expressed in siliques. Expression is highest in inflorescence and flower tissue.Transmission of mutant alleles to the progeny shows non mendelian segregation- a percentage of mutant alleles revert back to a previous parental (e.g. grandparental) wild type allele. It has been suggested that an RNA template driven or other extra-DNA genomic mechanism may be responsible for the non-mendelian inheritance of HTH. Reversion events in alleles at other loci have also been observed to occur in plants with an hth mutant background indicating a genome wide effect.
UniProt Gene Name
HTH
UniProt Synonym Gene Names
ACE
UniProt Protein Name
Protein HOTHEAD
UniProt Synonym Protein Names
Protein ADHESION OF CALYX EDGES
UniProt Primary Accession #
Q9S746
UniProt Secondary Accession #
Q9SXZ3
UniProt Related Accession #
Q9S746
UniProt Comments
Probable FAD-dependent enzyme. Involved in regulating post-genital organ fusion. Required to limit cellular interactions between contacting epidermal cells during floral development.
For research use only, not for clinical use.