NCBI Accession #
NP_192929.2
NCBI GenBank Nucleotide #
NM_117262.3
NCBI Official Full Name
cell cycle switch protein 52 A2
NCBI Official Symbol
CCS52A2
NCBI Official Synonym Symbols
cell cycle switch protein 52 A2; cell cycle switch protein 52 A2; FIZZY-RELATED 1; FZR1; T26M18.130; T26M18_130
NCBI Protein Information
cell cycle switch protein 52 A2
NCBI Summary
Encodes a putative activator of the anaphase-promoting complex/cyclosome. Promotes exit from the cell cycle and entry into the endocycle leading to endoreduplication. Mutation of this gene results in abnormal shoot apical meristem development. It likely regulates the development of meristems by indirectly interacting with WUS and CLV3.
UniProt Synonym Gene Names
CCS52A2; CDH1-1
UniProt Protein Name
Protein FIZZY-RELATED 1
UniProt Synonym Protein Names
Cell cycle switch protein CCS52A2
UniProt Primary Accession #
Q8VZS9
UniProt Secondary Accession #
Q9T060
UniProt Related Accession #
Q8VZS9
UniProt Comments
Activator protein that regulates the ubiquitin ligase activity and substrate specificity of the anaphase promoting complex/cyclosome (APC/C). Required for meristem organization and maintenance of quiescent center identity and stem cells.