NCBI Accession #
NP_567084.1
NCBI GenBank Nucleotide #
NM_115800.6
NCBI Official Full Name
farnesyltransferase A
NCBI Official Synonym Symbols
ATFTA; farnesyltransferase A; FARNESYLTRANSFERASE A; FARNESYLTRANSFERASE SUBUNIT A; PFT/PGGT-IALPHA; PLP; PLURIPETALA
NCBI Protein Information
farnesyltransferase A
NCBI Summary
Encodes the alpha-subunit shared between protein farnesyltransferase and protein geranylgeranyltransferase-I. Involved in protein prenylation: covalent attachment of the C-15 isoprene farnesyl or the C-20 isoprene geranylgeranyl groups to the C-terminal end of some proteins. Involved in shoot and flower meristem homeostasis, and response to ABA and drought. Also regulates leaf cell shape. Mutant is epistatic to era1.
UniProt Synonym Gene Names
GGTase-I-alpha
UniProt Protein Name
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
UniProt Synonym Protein Names
CAAX farnesyltransferase subunit alpha; FTase-alpha; Ras proteins prenyltransferase subunit alpha; Type I protein geranyl-geranyltransferase subunit alpha; GGTase-I-alpha
UniProt Primary Accession #
Q9LX33
UniProt Secondary Accession #
O65346
UniProt Related Accession #
Q9LX33
UniProt Comments
Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.