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Protein EARLY FLOWERING 4 (ELF4), Recombinant Protein
Cat: RP02025
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Protein EARLY FLOWERING 4 (ELF4)
Product Gene Name
ELF4 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MKRNGETKRR RNVAEEAEQG EDPAMWENLD RNFRQVQSVL DRNRSLIQQV NDNHQSRMAD NMSKNVALIQ ELNGNISKVV NMYSDLNTSF SSGFHGGKNG HDGGGAAGTR A
Sequence Positions
1-111, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
12,376 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Protein EARLY FLOWERING
NCBI/Uniprot Data
NCBI Accession #
NP_565922.1
NCBI GI #
18405258
NCBI GenBank Nucleotide #
NM_129566.2
NCBI GeneID
818596
NCBI Official Full Name
EARLY FLOWERING-like protein (DUF1313)
NCBI Official Symbol
ELF4
NCBI Official Synonym Symbols
EARLY FLOWERING 4; T28M21.24; T28M21_24
NCBI Protein Information
EARLY FLOWERING-like protein (DUF1313)
NCBI Summary
Encodes a novel nuclear 111 amino-acid phytochrome-regulated component of a negative feedback loop involving the circadian clock central oscillator components CCA1 and LHY. ELF4 is necessary for light-induced expression of both CCA1 and LHY, and conversely, CCA1 and LHY act negatively on light-induced ELF4 expression. ELF4 promotes clock accuracy and is required for sustained rhythms in the absence of daily light/dark cycles. It is involved in the phyB-mediated constant red light induced seedling de-etiolation process and may function to coregulate the expression of a subset of phyB-regulated genes.
UniProt Gene Name
ELF4
UniProt Synonym Gene Names
ARR08; ARR16; ARR19; ARR44; ARR80
UniProt Protein Name
Protein EARLY FLOWERING 4
UniProt Synonym Protein Names
Protein ARRHYTHMIC 44
UniProt Primary Accession #
O04211
UniProt Related Accession #
O04211
UniProt Comments
Component of the central CCA1/LHY-TOC1 feedback loop in the circadian clock that promotes clock accuracy and is required for sustained rhythms in the absence of daily light/dark cycles. Part of a corepressor complex consisting of ELF4, ELF3, and LUX involved in the transcriptional regulation of APRR9. Increases ELF3 nuclear distribution and localization in nuclear bodies. Required for responsiveness to continuous red, by regulating phytochrome B (phyB) signaling (including during seedling de-etiolation) and gene expression. Mediates both entrainment to an environmental cycle and circadian rhythm sustainability under constant conditions. Controls flowering time. Necessary for light-induced expression of both CCA1 and LHY.
For research use only, not for clinical use.