NCBI Accession #
NP_565099.1
NCBI GenBank Nucleotide #
NM_106164.3
NCBI Official Full Name
Brassinosteroid signaling positive regulator (BZR1) family protein
NCBI Official Symbol
BZR1
NCBI Official Synonym Symbols
BRASSINAZOLE-RESISTANT 1; F9E10.7; F9E10_7
NCBI Protein Information
Brassinosteroid signaling positive regulator (BZR1) family protein
NCBI Summary
Encodes a positive regulator of the brassinosteroid (BR) signalling pathway that mediates both downstream BR responses and negative feedback regulation of BR biosynthesis. There is evidence for phosphorylation-dependent nucleocytoplasmic shuttling of BZR1. GSK3-like kinases (including BIN2), 14-3-3 proteins, and the phosphatase BSU1 seem to participate in this process. Phosphorylation also appears to affect BZR1's transcriptional activities.
UniProt Synonym Gene Names
BIS2
UniProt Protein Name
Protein BRASSINAZOLE-RESISTANT 1
UniProt Synonym Protein Names
Protein BIN2 SUBSTRATE 2
UniProt Primary Accession #
Q8S307
UniProt Secondary Accession #
Q8VZD2; Q9C9Q2
UniProt Related Accession #
Q8S307
UniProt Comments
Transcriptional repressor that binds to the brassinosteroid (BR) response element (BRRE) 5'-CGTG(T/C)G-3' in gene promoter. Regulates positively the brassinosteroid-signaling pathway. Mediates downstream growth responses and negative feedback regulation of brassinosteroid biosynthesis. Promotes growth. Modulates ovule initiation and development by monitoring the expression of genes related to ovule development (e.g. HLL, ANT, and AP2).