NCBI Accession #
NP_568944.1
NCBI GenBank Nucleotide #
NM_125583.4
NCBI Official Full Name
Calcium-dependent phospholipid-binding Copine family protein
NCBI Official Symbol
BON1
NCBI Official Synonym Symbols
BON; BONZAI 1; COPINE 1; CPN1; K22G18.2; K22G18_2
NCBI Protein Information
Calcium-dependent phospholipid-binding Copine family protein
NCBI Summary
Encodes a plasma-membrane localized, copine-like protein, which is a member of a newly identified class of calcium-dependent, phospholipid binding proteins that are present in a wide range of organisms. Mutants exhibit temperature-sensitive growth defects and increased hypersensitive response where permissive conditions are low temperature (22 degrees Celsius) and low humidity. Gene is expressed at 22 but not at 28 (restrictive condition) degrees. Lethality of double mutants with BON3 can be partially suppressed by SNC1. Double mutants show defects in development that are genetically separable from hypersensitive/cell death response.
UniProt Synonym Gene Names
CPN1
UniProt Protein Name
Protein BONZAI 1
UniProt Synonym Protein Names
COPINE 1
UniProt Primary Accession #
Q941L3
UniProt Secondary Accession #
Q9FH53
UniProt Related Accession #
Q941L3
UniProt Comments
Negative regulator of cell death and defense responses. Negative regulator of several R genes, including SNC1. May have effects in promoting growth and development. May function in membrane trafficking and in fusion of vesicles with plasma membrane at low temperature. Exhibits calcium-dependent phospholipid binding properties.