NCBI Accession #
NP_175158.1
NCBI GenBank Nucleotide #
NM_103619.5
NCBI Official Full Name
20S proteasome alpha subunit F2
NCBI Official Symbol
PAF2
NCBI Official Synonym Symbols
20S proteasome alpha subunit F2; 20S PROTEASOME SUBUNIT PAF2; F8G22.3; F8G22_3
NCBI Protein Information
20S proteasome alpha subunit F2
NCBI Summary
Encodes 20S proteasome subunit PAF2 (PAF2).
UniProt Synonym Gene Names
PRC2B; PRS1
UniProt Protein Name
Proteasome subunit alpha type-1-B
UniProt Synonym Protein Names
20S proteasome alpha subunit F-2; Proteasome component 2B; Proteasome subunit alpha type-6
UniProt Primary Accession #
O23712
UniProt Related Accession #
O23712
UniProt Comments
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. May play a role in thiol biosynthesis and arsenic tolerance in association with PAF1/ARS5.