NCBI Accession #
NP_564633.2
NCBI GenBank Nucleotide #
NM_104228.3
NCBI Official Full Name
NAD-dependent epimerase/dehydratase family protein
NCBI Official Symbol
MUM4
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA MUCILAGE-MODIFIED 4; ARABIDOPSIS THALIANA RHAMNOSE BIOSYNTHESIS 2; ATMUM4; ATRHM2; F22G10.13; MUCILAGE-MODIFIED 4; RHAMNOSE BIOSYNTHESIS 2; RHM2
NCBI Protein Information
NAD-dependent epimerase/dehydratase family protein
NCBI Summary
encodes a putative NDP-L-rhamnose synthase, an enzyme required for the synthesis of the pectin rhamnogalacturonan I, the major component of Arabidopsis mucilage. Gene is involved in seed coat mucilage cell development. Mutant analyses suggest that MUM4 is required for complete mucilage synthesis, cytoplasmic rearrangement and seed coat development.
UniProt Synonym Gene Names
AtRHM2
UniProt Protein Name
Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM2
UniProt Synonym Protein Names
NDP-rhamnose synthase; Protein MUCILAGE-MODIFIED 4; Protein RHAMNOSE BIOSYNTHESIS 2; Rhamnose biosynthetic enzyme 2; AtRHM2; UDP-L-rhamnose synthase MUM4Including the following 2 domains:UDP-glucose 4,6-dehydratase
UniProt Primary Accession #
Q9LPG6
UniProt Related Accession #
Q9LPG6
UniProt Comments
Trifunctional enzyme involved in UDP-beta-L-rhamnose biosynthesis, a precursor of the primary cell wall components rhamnogalacturonan I (RG-I) and rhamnogalacturonan II (RG-II). Catalyzes the dehydration of UDP-glucose to form UDP-4-dehydro-6-deoxy-D-glucose followed by the epimerization of the C3' and C5' positions of UDP-4-dehydro-6-deoxy-D-glucose to form UDP-4-keto-beta-L-rhamnose and the reduction of UDP-4-keto-beta-L-rhamnose to yield UDP-beta-L-rhamnose (PubMed:17190829). Required for the normal seed coat epidermal development (PubMed:14671019).