Probable protein-S-isoprenylcysteine O-methyltransferase (ICMT), Recombinant Protein

Inquiry

Cat: RP10822

Species: Oryza sativa subsp. indica (Rice)

Datasheet:

Product Info

Full Product Name

Recombinant Oryza sativa subsp. indica Probable protein-S-isoprenylcysteine O-methyltransferase (ICMT)

Product Synonym Names

Recombinant Probable protein-S-isoprenylcysteine O-methyltransferase (ICMT); Probable protein-S-isoprenylcysteine O-methyltransferase EC= 2.1.1.100; Isoprenylcysteine carboxylmethyltransferase Prenylated protein carboxyl methyltransferase Prenylcysteine c

Product Gene Name

ICMT recombinant protein

Product Synonym Gene Name

ICMT; B0403H10-OSIGBa0105A11.23, OsI_016666

Purity

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Sequence

MAARAQAWLF AAALVIFHGS EYVLAAAFHG RRNVTATSLL ISKQYVLAMS FAMLEHLTEA LLFPELKEYW FVSYVGLVMV IIGEVIRKLA VVTAGRSFTH VIRIHYEDQH KLITHGVYRL MRHPGYSGFL IWAVGTQVML CNPLSTVAFT LVLWRFFSKR IPYEEFFLRQ FFGREYEEYA QKVHSGLPFI E

Sequence Positions

1-191

Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Molecular Weight

22,071 Da

Storage

Store at -20℃. For extended storage, store at -20 or -80℃.

Protein Family

Protein-S-isoprenylcysteine O-methyltransferase

NCBI/Uniprot Data

UniProt Gene Name

ICMT

UniProt Protein Name

Probable protein-S-isoprenylcysteine O-methyltransferase

UniProt Synonym Protein Names

Isoprenylcysteine carboxylmethyltransferase; Prenylated protein carboxyl methyltransferase; Prenylcysteine carboxyl methyltransferase

UniProt Entry Name

ICMT_ORYSI

UniProt Primary Accession #

A2XX73

UniProt Secondary Accession #

Q01HS5

UniProt Comments

Function: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues. Carboxyl methylation is a reversible and potentially regulated step in the post-translational modification of prenylated proteins By similarity.Catalytic activity: S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester.Cofactor: Divalent cations. Probably zinc By similarity.Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein By similarity. Sequence similarities: Belongs to the isoprenylcysteine O-methyltransferase family.

For research use only, not for clinical use.