NCBI Accession #
NP_001189742.1
NCBI GenBank Nucleotide #
NM_001202813.1
NCBI Official Full Name
glutathione peroxidase 3
NCBI Official Symbol
GPX3
NCBI Official Synonym Symbols
ATGPX3; glutathione peroxidase 3; T1O24.9
NCBI Protein Information
glutathione peroxidase 3
NCBI Summary
Glutathione peroxidase. Functions as both a redox transducer and a scavenger in abscisic acid and drought stress responses. Interacts with ABI2 and ABI1.
UniProt Protein Name
Probable glutathione peroxidase 3, mitochondrial
UniProt Primary Accession #
O22850
UniProt Related Accession #
O22850
UniProt Comments
May constitute a glutathione peroxidase-like protective system against oxidative stresses. Involved positively in abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, seed germination and inhibition of vegetative growth. Oxidizes and represses target proteins (e.g. the phosphatase activity of ABI1 and ABI2) when oxidized by H2O2, probably after ABA signaling. Modulates the calcium channel activity in guard cells in response to ABA or H2O2. Confers tolerance to drought stress, by enhancing the ABA-dependent stomatal closure.