NCBI Accession #
NP_172692.1
NCBI GenBank Nucleotide #
NM_101100.2
NCBI Official Full Name
LRR and NB-ARC domains-containing disease resistance protein
NCBI Official Symbol
SUMM2
NCBI Official Synonym Symbols
F5O11.34; F5O11_34; suppressor of mkk1 mkk2 2
NCBI Protein Information
LRR and NB-ARC domains-containing disease resistance protein
NCBI Summary
Encodes a NB-LRR protein SUMM2 involved in defense response to bacterium.
UniProt Protein Name
Disease resistance protein SUMM2
UniProt Synonym Protein Names
Disease resistance protein At1g12280
UniProt Primary Accession #
P60838
UniProt Secondary Accession #
Q9LNB5
UniProt Related Accession #
P60838
UniProt Comments
Disease resistance protein that mediates defense responses against the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000, and the virulent oomycete Hyaloperonospora arabidopsidis isolate Noco2. Becomes active when the MEKK1-MKK1-MKK2-MPK4 kinase cascade is disrupted by the microbial effector hopAI1. Does not seem to be required for the activation of MPK4 by flg22, or flg22-induced up-regulation of PAD3 (PubMed:22423965). Functions downstream of MEKK2/SUMM1 in immune responses, including cell death and defense responses (PubMed:22643122).