NCBI Accession #
NP_001234021.1
NCBI GenBank Nucleotide #
NM_001247092.2
NCBI Official Full Name
polygalacturonase-2
NCBI Official Synonym Symbols
PG; PG2A; PG-2B; PG-2a
NCBI Protein Information
polygalacturonase-2
NCBI Summary
This gene codes for polygalacturonase (PG) which is the major enzyme involved in pectin metabolism during fruit ripening. First genetically modified tomato, called the FLAVR SAVR tomato, was developed through the use of antisense RNA to regulate the expression of PG in ripening tomato. [provided by RefSeq, Jun 2016]
UniProt Synonym Gene Names
PG; PG2A; PG2B; PG
UniProt Protein Name
Polygalacturonase-2
UniProt Synonym Protein Names
PG-2A; PG-2B; Pectinase
UniProt Primary Accession #
P05117
UniProt Secondary Accession #
P94004; Q70Y18; Q7DM56
UniProt Related Accession #
P05117
UniProt Comments
Catalytic subunit of the polygalacturonase isozyme 1 and 2 (PG1 and PG2). Acts in concert with the pectinesterase, in the ripening process. Is involved in cell wall metabolism, specifically in polyuronide degradation. The depolymerization and solubilization of cell wall polyuronides mediated by PG2 during ripening seems to be limited by the beta subunit GP1, probably by recruiting PG2 to form PG1.