NCBI Accession #
NP_001119413.1
NCBI GenBank Nucleotide #
NM_001125941.1
NCBI Official Full Name
VEFS-Box of polycomb protein
NCBI Official Symbol
EMF2
NCBI Official Synonym Symbols
AT5G51240; AtEMF2; CYR1; CYTOKININ RESISTANT 1; EMBRYONIC FLOWER 2; MWD22.18; MWD22_18; VEF2
NCBI Protein Information
VEFS-Box of polycomb protein
NCBI Summary
Polycomb group protein with zinc finger domain involved in negative regulation of reproductive development. Forms a complex with FIE, CLF, and MSI1. This complex modulates the expression of target genes including AG, PI and AP3.
UniProt Protein Name
Polycomb group protein EMBRYONIC FLOWER 2
UniProt Primary Accession #
Q8L6Y4
UniProt Secondary Accession #
Q53XQ5; Q93V59; Q9LU50; Q9LU51
UniProt Related Accession #
Q8L6Y4
UniProt Comments
Polycomb group (PcG) protein. Involved in flowering processes by repressing unknown target genes and preventing reproductive development. Participates in polycomb group (PcG) protein complex-mediated (probably in complex with EMF1) silencing of the flower homeotic genes AGAMOUS (AG), PISTILLATA (PI), and APETALA3 (AP3), as well as of some regulatory genes such as ABSCISIC ACID INSENSITIVE3 (ABI3), LONG VEGETATIVE PHASE1 (LOV1), and FLOWERING LOCUS C (FLC) during vegetative development, by mediating trimethylation of histone 3 lysine 27 on the AG chromatin (H3K27me3). PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility.