NCBI Accession #
NP_196874.1
NCBI GenBank Nucleotide #
NM_121373.4
NCBI Official Full Name
polyamine oxidase 1
NCBI Official Symbol
PAO1
NCBI Official Synonym Symbols
APAO; ATPAO1; MSH12.17; MSH12_17; polyamine oxidase 1
NCBI Protein Information
polyamine oxidase 1
NCBI Summary
Encodes a protein with polyamine oxidase activity. The mRNA of this gene is only expressed in very low amounts in the organs where it was detected (light-grown plants).
UniProt Synonym Gene Names
PAO; AtPAO1
UniProt Protein Name
Polyamine oxidase 1
UniProt Synonym Protein Names
N(1)-acetylpolyamine oxidase; Spermine oxidase
UniProt Primary Accession #
Q9FNA2
UniProt Secondary Accession #
Q7FL79
UniProt Related Accession #
Q9FNA2
UniProt Comments
Flavoenzyme that catalyzes the oxidation of the secondary amino group of spermine, norspermine and N1-acetylspermine. Substrate preference is norspermine > spermine > N1-acetylspermine. No activity detected when putrescine, spermidine or N1-acetylspermidine are used as substrates. Plays an important role in the regulation of polyamine intracellular concentration.