NCBI Accession #
NP_173690.1
NCBI GenBank Nucleotide #
NM_102123.4
NCBI Official Full Name
poly(A) binding protein 3
NCBI Official Symbol
PAB3
NCBI Official Synonym Symbols
poly(A) binding protein 3; POLY(A) BINDING PROTEIN 3; T22J18.7; T22J18_7
NCBI Protein Information
poly(A) binding protein 3
NCBI Summary
Putative poly(A) binding protein May there fore function in posttranscriptional regulation, including mRNA turnover and translational initiation. Expression detected only in floral organs.
UniProt Synonym Gene Names
PABP-3; Poly(A)-binding protein 3
UniProt Protein Name
Polyadenylate-binding protein 3
UniProt Primary Accession #
O64380
UniProt Secondary Accession #
O80546; Q9FYS4
UniProt Related Accession #
O64380
UniProt Comments
Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the cytoplasm, affects both translation and mRNA decay. Inhibits the polyadenylated RNA degradation by the Rrp41p 3'-->5' exonuclease in vitro. Binds with the 5'UTRs of PAB2, PAB3 and with a lower affinity with the 5'UTR of PAB5.