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Polyadenylate-binding protein 2 (PAB2), Recombinant Protein
Cat: RP01921
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Polyadenylate-binding protein 2 (PAB2) , partial
Product Gene Name
PAB2 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
68,672 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Proteasome
NCBI/Uniprot Data
NCBI Accession #
NP_195137.5
NCBI GI #
240256156
NCBI GenBank Nucleotide #
NM_119572.7
NCBI GeneID
829557
NCBI Official Full Name
poly(A) binding protein 2
NCBI Official Symbol
PAB2
NCBI Official Synonym Symbols
ARABIDOPSIS POLY(A) BINDING 2; ATPAB2; F28A23.130; F28A23_130; PABP2; poly(A) binding protein 2; POLY(A) BINDING PROTEIN 2; POLY(A)-BINDING PROTEIN 2
NCBI Protein Information
poly(A) binding protein 2
NCBI Summary
Putative poly-A binding protein. Member of a gene family .Expressed in stele and root meristem and post-fertilization ovules.Member of the class II family of PABP proteins.
UniProt Gene Name
PAB2
UniProt Synonym Gene Names
PABP-2; Poly(A)-binding protein 2
UniProt Protein Name
Polyadenylate-binding protein 2
UniProt Primary Accession #
P42731
UniProt Secondary Accession #
Q8RXR5
UniProt Related Accession #
P42731
UniProt Comments
Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the cytoplasm, affects both translation and mRNA decay. Stimulates translation by interaction with translation initiation factor eIF4G, a subunit of the cap-binding complex eIF4F, bringing the 5'- and 3'-ends of the mRNA in proximity. The formation of this circular mRNP structure appears to be critical for the synergistic effects of the cap and the poly(A) tail in facilitating translation initiation, recycling of ribosomes, and mRNA stability. During infection with potyvirus TuMV, acts as a potential integral component of the viral replicase complex that could play an important role in the regulation of potyviral RNA-dependent RNA polymerase (RdRp).
For research use only, not for clinical use.