Plant-Based Protein Expression Platform

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Plant-Based Protein Expression Platform

With a deep understanding of plants and years of experience in protein expression, CD BioSciences has a variety of specialized plant-based recombinant protein expression systems that offer unmatched production speed, high scalability, low cost, and eukaryotic protein modification capabilities.

Figure 1. Schematic representation of technologies available in plant-based platforms for the production of recombinant biopharmaceuticals. – CD BioSciences Figure 1. Schematic representation of technologies available in plant-based platforms for the production of recombinant biopharmaceuticals. (Shanmugaraj, B., et al., 2021)

In recent years, the use of plants to express and produce exogenous proteins has been applied to a wide range of medical, food, and industrial proteins and enzymes. Our platform is capable of expressing proteins from animals, bacteria, viruses, and plants themselves, including a wide range of antibodies, enzymes, kinetic disorders, plasma proteins, and vaccines.

Tobacco transient/stable expression system.

Tobacco transient/stable expression system

Tobacco cell-free expression system.

Tobacco cell-free expression system

Lettuce transient/stable expression system.

Lettuce transient/stable expression system

Oryza endosperm-specific expression system.

Oryza endosperm-specific expression system

Plant cell suspension-based expression system.

Plant cell suspension-based expression system

Plant hairy root-based expression system.

Plant hairy root-based expression system

Microalgae expression system.

Microalgae expression system

Wheat germ cell cell-free expression .

Wheat germ cell cell-free expression

Chloroplast transformation system.

Chloroplast transformation system

Our Platforms

The production of recombinant proteins by plants as bioreactors has lots of advantages

  • Easy gene transformation, high success rate, short cycle time, high expression, easy purification, and fast yield.
  • Stable genetic traits of homogeneous progeny are obtained from the self-crossing of transgenic plants, which in turn can accumulate multiple genes in the plant.
  • No threat of phage contamination backflow, and little contamination by animal pathogens.
  • Compared with other expression systems, the upstream production cost of plant expression systems is low and more suitable for mass production.

Why Choose Us?

  • We have a wide range of plant species for vaccine expression.
  • We offer a wide range of proven viral expression vectors.
  • We have comprehensive transient or stable conversion systems.
  • We can produce to satisfy specific requirements.

CD BioSciences provides innovative solutions for the efficient production of recombinant proteins using plant systems, establishing robust and streamlined processes covering gene synthesis, vector construction, transformation, protein expression optimization, and protein purification. Please contact us if you are interested in our platforms to help drive progress through the power of plants in a variety of fields including pharmaceuticals, biotechnology, agriculture, and environmental science.

References

  1. Shanmugaraj, B., et al. (2021). Biotechnological Insights on the Expression and Production of Antimicrobial Peptides in Plants. Molecules. 26, 4032.
  2. Eidenberger, L., et al. (2023). Plant-based biopharmaceutical engineering. Nat Rev Bioeng. 1, 426-439.

For research use only, not for clinical use.